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Enantioselective Palladium-Catalyzed Alkenylation of Trisubstituted Alkenols to form Allylic Quaternary Centers

In this report, we describe the generation of remote allylic quaternary stereocenters β, γ, and δ relative to a carbonyl in high enantioselectivity. We utilize a redox-relay Heck reaction between alkenyl triflates and acyclic trisubstituted alkenols of varying chain-lengths. A wide array of terminal...

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Bibliografski detalji
Izdano u:J Am Chem Soc
Glavni autori: Patel, Harshkumar H., Sigman, Matthew S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152571/
https://ncbi.nlm.nih.gov/pubmed/27768842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09649
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