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Molecular basis for the broad substrate selectivity of a peptide prenyltransferase

The cyanobactin prenyltransferases catalyze a series of known or unprecedented reactions on millions of different substrates, with no easily observable recognition motif and exquisite regioselectivity. Here we define the basis of broad substrate tolerance for the otherwise uncharacterized TruF famil...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Hao, Yue, Pierce, Elizabeth, Roe, Daniel, Morita, Maho, McIntosh, John A., Agarwal, Vinayak, Cheatham, Thomas E., Schmidt, Eric W., Nair, Satish K.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150373/
https://ncbi.nlm.nih.gov/pubmed/27872314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609869113
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