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Interactions of divalent cations with calcium binding sites of BK channels reveal independent motions within the gating ring
Large-conductance voltage- and calcium-activated K(+) (BK) channels are key physiological players in muscle, nerve, and endocrine function by integrating intracellular Ca(2+) and membrane voltage signals. The open probability of BK channels is regulated by the intracellular concentration of divalent...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5150367/ https://ncbi.nlm.nih.gov/pubmed/27872281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611415113 |
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