Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction

Hsp70 chaperones assist de novo folding of newly synthesized proteins in all cells. In yeast, the specialized Hsp70 Ssb directly binds to ribosomes. The structural basis and functional mode of recruitment of Ssb to ribosomes is not understood. Here, we present the molecular details underlying riboso...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Hanebuth, Marie A., Kityk, Roman, Fries, Sandra J., Jain, Alok, Kriel, Allison, Albanese, Veronique, Frickey, Tancred, Peter, Christine, Mayer, Matthias P., Frydman, Judith, Deuerling, Elke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150220/
https://ncbi.nlm.nih.gov/pubmed/27917864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13695
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