Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction

Hsp70 chaperones assist de novo folding of newly synthesized proteins in all cells. In yeast, the specialized Hsp70 Ssb directly binds to ribosomes. The structural basis and functional mode of recruitment of Ssb to ribosomes is not understood. Here, we present the molecular details underlying riboso...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Hanebuth, Marie A., Kityk, Roman, Fries, Sandra J., Jain, Alok, Kriel, Allison, Albanese, Veronique, Frickey, Tancred, Peter, Christine, Mayer, Matthias P., Frydman, Judith, Deuerling, Elke
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150220/
https://ncbi.nlm.nih.gov/pubmed/27917864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13695
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