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The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis
In eukaryotic cells a molecular chaperone network associates with translating ribosomes, assisting the maturation of emerging nascent polypeptides. Hsp70 is perhaps the major eukaryotic ribosome-associated chaperone and the first reported to bind cotranslationally to nascent chains. However, little...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553497/ https://ncbi.nlm.nih.gov/pubmed/23332755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.12.001 |
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