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Principles of cotranslational ubiquitination and quality control at the ribosome
Achieving efficient cotranslational folding of their complex proteomes poses a challenge for eukaryotic cells. Nascent polypeptides emerging vectorially from the ribosome often cannot fold stably and may be susceptible to misfolding and degradation. The extent to which nascent chains are subject to...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3886275/ https://ncbi.nlm.nih.gov/pubmed/23583075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.03.010 |
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