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Comment on “Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling”
Jan et al. propose that ribosomes translating secretome mRNAs are recruited to the ER upon emergence of the signal peptide and return to the cytosol following termination. A thorough accounting of their controls demonstrates, however, that ribosomes are retained on the ER through many full cycles of...
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| Publicado no: | Science |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862200/ https://ncbi.nlm.nih.gov/pubmed/26068841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa7257 |
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