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Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling

Nearly all mitochondrial proteins are nuclear-encoded and are targeted to their mitochondrial destination from the cytosol. Here, we used proximity-specific ribosome profiling to comprehensively measure translation at the mitochondrial surface in yeast. Most inner membrane proteins were co-translati...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Williams, Christopher C., Jan, Calvin H., Weissman, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263316/
https://ncbi.nlm.nih.gov/pubmed/25378625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1257522
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