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Ribosome Profiling Reveals Pervasive Translation Outside of Annotated Protein-Coding Genes

Ribosome profiling suggests that ribosomes occupy many regions of the transcriptome thought to be non-coding, including 5′ UTRs and lncRNAs. Apparent ribosome footprints outside of protein-coding regions raise the possibility of artifacts unrelated to translation, particularly when they occupy multi...

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Bibliographische Detailangaben
Hauptverfasser: Ingolia, Nicholas T., Brar, Gloria A., Stern-Ginossar, Noam, Harris, Michael S., Talhouarne, Gaëlle J. S., Jackson, Sarah E., Wills, Mark R., Weissman, Jonathan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216110/
https://ncbi.nlm.nih.gov/pubmed/25159147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.045
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