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GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation

G protein-coupled receptor kinases (GRKs) represent a class of proteins that classically phosphorylate agonist-activated G protein-coupled receptors, leading to uncoupling of the receptor from further G protein activation. Recently, we have reported that the heterotrimeric G protein α-subunit, Gαq/1...

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Pubblicato in:EMBO J
Autori principali: Usui, Isao, Imamura, Takeshi, Satoh, Hiroaki, Huang, Jie, Babendure, Jennie L, Hupfeld, Christopher J, Olefsky, Jerrold M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15241473/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600297
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