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The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK

Nischarin, a novel intracellular protein, was originally identified as a binding partner for the α5β1 integrin. Here we show that Nischarin also interacts with members of the PAK family of kinases. The amino terminus of Nischarin preferentially binds to the carboxy-terminal domain of PAK1 when the k...

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Hlavní autoři: Alahari, Suresh K, Reddig, Peter J, Juliano, Rudy L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC514951/
https://ncbi.nlm.nih.gov/pubmed/15229651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600291
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