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Nischarin Inhibits LIM Kinase To Regulate Cofilin Phosphorylation and Cell Invasion
Nischarin is a novel protein that regulates cell migration by inhibiting p21-activated kinase (PAK). LIM kinase (LIMK) is a downstream effector of PAK, and it is known to play an important role in cell invasion. Here we show that nischarin also associates with LIMK to inhibit LIMK activation, cofili...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology (ASM)
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423293/ https://ncbi.nlm.nih.gov/pubmed/18332102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01832-07 |
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