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The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK

Nischarin, a novel intracellular protein, was originally identified as a binding partner for the α5β1 integrin. Here we show that Nischarin also interacts with members of the PAK family of kinases. The amino terminus of Nischarin preferentially binds to the carboxy-terminal domain of PAK1 when the k...

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Detalhes bibliográficos
Main Authors: Alahari, Suresh K, Reddig, Peter J, Juliano, Rudy L
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514951/
https://ncbi.nlm.nih.gov/pubmed/15229651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600291
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