Integrin-binding Protein Nischarin Interacts with Tumor Suppressor Liver Kinase B1 (LKB1) to Regulate Cell Migration of Breast Epithelial Cells

Biallelic inactivation of LKB1, a serine/threonine kinase, has been detected in 30% of lung adenocarcinomas, and inhibition of breast tumor growth has been demonstrated. We have identified the tumor suppressor, Nischarin, as a novel binding partner of LKB1. Our mapping analysis shows that the N term...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jain, Prachi, Baranwal, Somesh, Dong, Shengli, Struckhoff, Amanda P., Worthylake, Rebecca A., Alahari, Suresh K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668711/
https://ncbi.nlm.nih.gov/pubmed/23572524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418103
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