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Nischarin Inhibits LIM Kinase To Regulate Cofilin Phosphorylation and Cell Invasion

Nischarin is a novel protein that regulates cell migration by inhibiting p21-activated kinase (PAK). LIM kinase (LIMK) is a downstream effector of PAK, and it is known to play an important role in cell invasion. Here we show that nischarin also associates with LIMK to inhibit LIMK activation, cofili...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ding, Yuemin, Milosavljevic, Tanja, Alahari, Suresh K.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423293/
https://ncbi.nlm.nih.gov/pubmed/18332102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01832-07
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