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Quantitation of polymyxin-lipopolysaccharide interactions using an image-based fluorescent probe

The frequency of polymyxin-resistant pathogenic Gram-negative bacteria appearing in the clinic is increasing, and the consequences are largely mediated by modification of lipopolysaccharide (LPS) in the outer membrane. As polymyxins exert their antibacterial effect by binding to LPS, understanding t...

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Dades bibliogràfiques
Publicat a:J Pharm Sci
Autors principals: McInerney, MP, Roberts, KD, Thompson, PE, Li, J, Nation, RL, Velkov, T, Nicolazzo, JA
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5149457/
https://ncbi.nlm.nih.gov/pubmed/26869441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2015.10.028
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