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Quantitation of polymyxin-lipopolysaccharide interactions using an image-based fluorescent probe
The frequency of polymyxin-resistant pathogenic Gram-negative bacteria appearing in the clinic is increasing, and the consequences are largely mediated by modification of lipopolysaccharide (LPS) in the outer membrane. As polymyxins exert their antibacterial effect by binding to LPS, understanding t...
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| Publicado no: | J Pharm Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5149457/ https://ncbi.nlm.nih.gov/pubmed/26869441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2015.10.028 |
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