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Evaluation of an amino acid residue critical for the specificity and activity of human Gb3/CD77 synthase
Human Gb3/CD77 synthase (α1,4-galactosyltransferase) is the only known glycosyltransferase that changes acceptor specificity because of a point mutation. The enzyme, encoded by A4GALT locus, is responsible for biosynthesis of Gal(α1–4)Gal moiety in Gb3 (CD77, P(k) antigen) and P1 glycosphingolipids....
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| Publicado no: | Glycoconj J |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5149393/ https://ncbi.nlm.nih.gov/pubmed/27538840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-016-9716-9 |
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