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Muscleblind proteins regulate alternative splicing
Although the muscleblind (MBNL) protein family has been implicated in myotonic dystrophy (DM), a specific function for these proteins has not been reported. A key feature of the RNA-mediated pathogenesis model for DM is the disrupted splicing of specific pre-mRNA targets. Here we demonstrate that MB...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514918/ https://ncbi.nlm.nih.gov/pubmed/15257297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600300 |
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