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BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks

Fanconi anaemia (FA) and Bloom syndrome (BS) are autosomal recessive diseases characterised by chromosome fragility and cancer proneness. Here, we report that BLM and the FA pathway are activated in response to both crosslinked DNA and replication fork stall. We provide evidence that BLM and FANCD2...

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Main Authors: Pichierri, Pietro, Franchitto, Annapaola, Rosselli, Filippo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC514912/
https://ncbi.nlm.nih.gov/pubmed/15257300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600277
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