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Conserved mechanism of conformational stability and dynamics in G-protein-coupled receptors

GPCRs are transmembrane receptors involved in diverse biological functions. Despite the diversity in their amino acid sequences, class A GPCRs exhibit a conserved structural topology and possibly common mechanism of receptor activation. To understand how this high sequence diversity translates to a...

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Dettagli Bibliografici
Pubblicato in:J Chem Theory Comput
Autori principali: Bhattacharya, Supriyo, Salomon-Ferrer, Romelia, Lee, Sangbae, Vaidehi, Nagarajan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148705/
https://ncbi.nlm.nih.gov/pubmed/27709935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b00618
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