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Tetracyclic Indolines as A Novel Class of β-Lactam-Selective Resistance-Modifying Agent for MRSA

Antibiotic-resistant bacterial infections have seen a marked increase in recent years, while antibiotic discovery has waned. Resistance-modifying agents (RMA) offer an intriguing alternative strategy to fight against resistant bacteria. Here we report the discovery, antibiotic profiling, and structu...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Zhu, Yugen, Cleaver, Lakota, Wang, Wei, Podoll, Jessica D., Walls, Shane, Jolly, Austin, Wang, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148702/
https://ncbi.nlm.nih.gov/pubmed/27657810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.09.034
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