Structure–Activity Relationship Studies of the Tricyclic Indoline Resistance-Modifying Agent

[Image: see text] Previously we discovered a tricyclic indoline, N-[2-(6-bromo-4-methylidene-2,3,4,4a,9,9a-hexahydro-1H-carbazol-4a-yl)ethyl]-4-chlorobenzene-1-sulfonamide (1, Of1), from bioinspired synthesis of a highly diverse polycyclic indoline alkaloid library, that selectively resensitizes met...

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Bibliografiske detaljer
Main Authors: Chang, Le, Podoll, Jessica D., Wang, Wei, Walls, Shane, O’Rourke, Courtney P., Wang, Xiang
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018117/
https://ncbi.nlm.nih.gov/pubmed/24694192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500146g
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