Discovery and Initial Structure-Activity Relationships of N-Benzyl Tricyclic Indolines as Antibacterials for Methicillin-Resistant Staphylococcus aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent drug resistant bacteria. In 2012, over 11,000 fatalities in the United States were directly attributable to MRSA. In an effort to develop novel structural and mechanistic classes of antibacterial agents to fight against...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Michael Barbour, P., Podoll, Jessica D., Marholz, Laura J., Wang, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963016/
https://ncbi.nlm.nih.gov/pubmed/25466183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.10.094
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