Discovery of Novel Wall Teichoic Acid Inhibitors as Effective anti-MRSA β-lactam Combination Agents

Innovative strategies are needed to combat drug resistance associated with methicillin-resistant Staphylococcus aureus (MRSA). Here, we investigate the potential of wall teichoic acid (WTA) biosynthesis inhibitors as combination agents to restore β-lactam efficacy against MRSA. Performing a whole ce...

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Hauptverfasser: Wang, Hao, Gill, Charles J., Lee, Sang H., Mann, Paul, Zuck, Paul, Meredith, Timothy C., Murgolo, Nicholas, She, Xinwei, Kales, Susan, Liang, Lianzhu, Liu, Jenny, Wu, Jin, Maria, John Santa, Su, Jing, Pan, Jianping, Hailey, Judy, Mcguinness, Debra, Tan, Christopher M., Flattery, Amy, Walker, Suzanne, Black, Todd, Roemer, Terry
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762323/
https://ncbi.nlm.nih.gov/pubmed/23438756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.11.013
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