ロード中...
“Marker of Self” CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors
Lentiviruses infect many cell types and are now widely used for gene delivery in vitro, but in vivo uptake of these foreign vectors by macrophages is a limitation. Lentivectors are produced here from packaging cells that overexpress “Marker of Self” CD47, which inhibits macrophage uptake of cells wh...
保存先:
| 出版年: | Mol Ther Methods Clin Dev |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5148596/ https://ncbi.nlm.nih.gov/pubmed/28053997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.80 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|