Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific ‘Marker of Self’ CD47, and target physical properties

Professional phagocytes of the mononuclear phagocyte system (MPS), especially ubiquitous macrophages, are commonly thought to engulf or not a target based strictly on ‘eat me’ molecules such as Antibodies. The target might be a viable ‘self’ cell or a drug-delivering nanoparticle, or it might be a c...

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Vydáno v:Curr Opin Immunol
Hlavní autoři: Sosale, Nisha G, Spinler, Kyle R, Alvey, Cory, Discher, Dennis E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553123/
https://ncbi.nlm.nih.gov/pubmed/26172292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.06.013
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