SRI-286, a Thiosemicarbazole, in Combination with Mefloquine and Moxifloxacin for Treatment of Murine Mycobacterium avium Complex Disease

Treatment of Mycobacterium avium disease remains challenging when macrolide resistance develops. We infected C57 beige mice and treated them with mefloquine, SRI-286, and moxifloxacin. SRI-286 (80 mg/kg) was bactericidal in the liver. Mefloquine plus moxifloxacin or mefloquine plus SRI-286 were bett...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bermudez, Luiz E., Kolonoski, Peter, Seitz, Lianne E., Petrofsky, Mary, Reynolds, Robert, Wu, Martin, Young, Lowell S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC514788/
https://ncbi.nlm.nih.gov/pubmed/15328125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3556-3558.2004
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