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A (99m)Tc-Labelled Tetrazine for Bioorthogonal Chemistry. Synthesis and Biodistribution Studies with Small Molecule trans-Cyclooctene Derivatives
A convenient strategy to radiolabel a hydrazinonicotonic acid (HYNIC)-derived tetrazine with (99m)Tc was developed, and its utility for creating probes to image bone metabolism and bacterial infection using both active and pretargeting strategies was demonstrated. The (99m)Tc-labelled HYNIC-tetrazin...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5147877/ https://ncbi.nlm.nih.gov/pubmed/27936007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167425 |
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