Disposition of Posaconazole following Single-Dose Oral Administration in Healthy Subjects

Posaconazole is a potent, broad-spectrum triazole antifungal agent currently in clinical development for the treatment of refractory invasive fungal infections. Eight healthy male subjects received a single 399-mg (81.7 μCi) oral dose of [(14)C]posaconazole after consuming a high-fat breakfast. Urin...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Krieter, Philip, Flannery, Brian, Musick, Timothy, Gohdes, Mark, Martinho, Monika, Courtney, Rachel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15328123/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.9.3543-3551.2004
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