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Disposition of Posaconazole following Single-Dose Oral Administration in Healthy Subjects
Posaconazole is a potent, broad-spectrum triazole antifungal agent currently in clinical development for the treatment of refractory invasive fungal infections. Eight healthy male subjects received a single 399-mg (81.7 μCi) oral dose of [(14)C]posaconazole after consuming a high-fat breakfast. Urin...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514780/ https://ncbi.nlm.nih.gov/pubmed/15328123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3543-3551.2004 |
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