Disposition of Posaconazole following Single-Dose Oral Administration in Healthy Subjects

Posaconazole is a potent, broad-spectrum triazole antifungal agent currently in clinical development for the treatment of refractory invasive fungal infections. Eight healthy male subjects received a single 399-mg (81.7 μCi) oral dose of [(14)C]posaconazole after consuming a high-fat breakfast. Urin...

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Detalhes bibliográficos
Main Authors: Krieter, Philip, Flannery, Brian, Musick, Timothy, Gohdes, Mark, Martinho, Monika, Courtney, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514780/
https://ncbi.nlm.nih.gov/pubmed/15328123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.9.3543-3551.2004
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