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Enantioselective disposition of hydroxychloroquine after a single oral dose of the racemate to healthy subjects.

1. Stereoselectivity in the disposition of hydroxychloroquine was investigated in 23 healthy males following a single oral dose of 200 mg racemic HCQ (rac-HCQ) sulphate. Total concentrations (R+S) and R/S ratios of HCQ and its metabolites were measured by stereoselective h.p.l.c. 2. HCQ was detected...

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Hlavní autoři: Ducharme, J, Fieger, H, Ducharme, M P, Khalil, S K, Wainer, I W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365171/
https://ncbi.nlm.nih.gov/pubmed/8562294
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