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Oral Treatment of Murine Cytomegalovirus Infections with Ether Lipid Esters of Cidofovir
To improve the oral bioavailability of cidofovir (CDV), a series of ether lipid ester prodrugs were synthesized and evaluated for activity against murine cytomegalovirus (MCMV) infection. Four of these analogs, hexadecyloxypropyl (HDP)-CDV, octadecyloxyethyl (ODE)-CDV, oleyloxyethyl (OLE)-CDV, and o...
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| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15328119/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.9.3516-3522.2004 |
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