A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO

Glycosylphosphatidylinositol-anchored proteins (GPI-APs) can be shed from the cell membrane by GPI cleavage. In this study, we report a novel GPI-processing enzyme, termed post-glycosylphosphatidylinositol attachment to proteins 6 (PGAP6), which is a GPI-specific phospholipase A2 mainly localized at...

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Vydáno v:J Cell Biol
Hlavní autoři: Lee, Gun-Hee, Fujita, Morihisa, Takaoka, Katsuyoshi, Murakami, Yoshiko, Fujihara, Yoshitaka, Kanzawa, Noriyuki, Murakami, Kei-ichi, Kajikawa, Eriko, Takada, Yoko, Saito, Kazunobu, Ikawa, Masahito, Hamada, Hiroshi, Maeda, Yusuke, Kinoshita, Taroh
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147002/
https://ncbi.nlm.nih.gov/pubmed/27881714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605121
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