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Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain

Many eukaryotic proteins are anchored to the cell surface via the glycolipid glycosylphosphatidylinositol (GPI). Mammalian GPIs have a conserved core but exhibit diverse N-acetylgalactosamine (GalNAc) modifications, which are added via a yet unresolved process. Here we identify the Golgi-resident GP...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hirata, Tetsuya, Mishra, Sushil K., Nakamura, Shota, Saito, Kazunobu, Motooka, Daisuke, Takada, Yoko, Kanzawa, Noriyuki, Murakami, Yoshiko, Maeda, Yusuke, Fujita, Morihisa, Yamaguchi, Yoshiki, Kinoshita, Taroh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785973/
https://ncbi.nlm.nih.gov/pubmed/29374258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02799-0
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