High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer.

DNA methylation abnormalities occur consistently in human neoplasia including widespread hypomethylation and more recently recognized local increases in DNA methylation that hold potential for gene inactivation events. To study this imbalance further, we have cloned and localized to chromosome 19 a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	el-Deiry, W S, Nelkin, B D, Celano, P, Yen, R W, Falco, J P, Hamilton, S R, Baylin, S B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2014266/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3470
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