Pleiotrophin transforms NIH 3T3 cells and induces tumors in nude mice.
The pleiotrophin (PTN) gene (Ptn) encodes an 18-kDa protein that is highly conserved among mammalian species and that functions as a weak mitogen and promotes neurite-outgrowth activity in vitro. To further investigate the role PTN plays in regulating cell growth, we overexpressed the bovine PTN cDN...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8421705/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.2.679 |
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