High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer.

DNA methylation abnormalities occur consistently in human neoplasia including widespread hypomethylation and more recently recognized local increases in DNA methylation that hold potential for gene inactivation events. To study this imbalance further, we have cloned and localized to chromosome 19 a...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	el-Deiry, W S, Nelkin, B D, Celano, P, Yen, R W, Falco, J P, Hamilton, S R, Baylin, S B
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1991
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2014266/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.8.3470
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