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Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O(2) regulation of erythrocyte properties
Functional studies have shown that the oxygenation state of the erythrocyte regulates many important pathways, including glucose metabolism, membrane mechanical stability, and cellular adenosine triphosphate (ATP) release. Deoxyhemoglobin (deoxyHb), but not oxyhemoglobin, binds avidly and reversibly...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5146745/ https://ncbi.nlm.nih.gov/pubmed/27688804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-692079 |
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