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Reassessing random-coil statistics in unfolded proteins
The Gaussian-distributed random coil has been the dominant model for denatured proteins since the 1950s, and it has long been interpreted to mean that proteins are featureless, statistical coils in 6 M guanidinium chloride. Here, we demonstrate that random-coil statistics are not a unique signature...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514656/ https://ncbi.nlm.nih.gov/pubmed/15314216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404236101 |
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