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Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
Constitutive activation of signal transducer and activator of transcription 3 (Stat3) has been found in a wide spectrum of human malignancies. Here, we have assessed the effect of Stat3 deficiency on skin tumor development using the 2-stage chemical carcinogenesis model. The epidermis of Stat3-defic...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514583/ https://ncbi.nlm.nih.gov/pubmed/15343391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421032 |
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