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Maturational differences in lung NF-κB activation and their role in tolerance to hyperoxia

Neonatal rodents are more tolerant to hyperoxia than adults. We determined whether maturational differences in lung NF-κB activation could account for the differences. After hyperoxic exposure (O(2) > 95%), neonatal (<12 hours old) lung NF-κB binding was increased and reached a maximum between...

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Main Authors: Yang, Guang, Abate, Aida, George, Adia G., Weng, Yi-Hao, Dennery, Phyllis A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC514581/
https://ncbi.nlm.nih.gov/pubmed/15343385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419300
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