IκBβ-Mediated NF-κB Activation Confers Protection against Hyperoxic Lung Injury

Supplemental oxygen is frequently used in an attempt to improve oxygen delivery; however, prolonged exposure results in damage to the pulmonary endothelium and epithelium. Although NF-κB has been identified as a redox-responsive transcription factor, whether NF-κB activation exacerbates or attenuate...

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Bibliographische Detailangaben
Hauptverfasser: Michaelis, Katherine A., Agboke, Fadeke, Liu, Thanh, Han, Kristie, Muthu, Manasa, Galambos, Csaba, Yang, Guang, Dennery, Phyllis A., Wright, Clyde J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930955/
https://ncbi.nlm.nih.gov/pubmed/24066808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0303OC
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