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Hyperoxia-induced NF-κB activation occurs via a maturationally sensitive atypical pathway

NF-κB activation is exaggerated in neonatal organisms after oxidant and inflammatory insults, but the reason for this and the downstream effects are unclear. We hypothesized that specific phosphorylation patterns of IκBα could account for differences in NF-κB activation in hyperoxia-exposed fetal an...

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Autori principali: Wright, Clyde J., Zhuang, Tiangang, La, Ping, Yang, Guang, Dennery, Phyllis A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660217/
https://ncbi.nlm.nih.gov/pubmed/19074556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90499.2008
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