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Endotoxin leads to rapid subcellular re-localization of hepatic RXRα: A novel mechanism for reduced hepatic gene expression in inflammation
BACKGROUND: Lipopolysaccharide (LPS) treatment of animals down-regulates the expression of hepatic genes involved in a broad variety of physiological processes, collectively known as the negative hepatic acute phase response (APR). Retinoid X receptor α (RXRα), the most highly expressed RXR isoform...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
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BioMed Central
2004
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514570/ https://ncbi.nlm.nih.gov/pubmed/15312234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-1336-2-4 |
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