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PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase

Chronic activation of the phosphoinositide 3-kinase (PI3K)/PTEN signal transduction pathway contributes to metastatic cell growth, but up to now effectors mediating this response are poorly defined. By simulating chronic activation of PI3K signaling experimentally, combined with three-dimensional (3...

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Bibliografiske detaljer
Main Authors: Leenders, Frauke, Möpert, Kristin, Schmiedeknecht, Anett, Santel, Ansgar, Czauderna, Frank, Aleku, Manuela, Penschuck, Silke, Dames, Sibylle, Sternberger, Maria, Röhl, Thomas, Wellmann, Axel, Arnold, Wolfgang, Giese, Klaus, Kaufmann, Jörg, Klippel, Anke
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514518/
https://ncbi.nlm.nih.gov/pubmed/15282551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600345
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