PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase

Chronic activation of the phosphoinositide 3-kinase (PI3K)/PTEN signal transduction pathway contributes to metastatic cell growth, but up to now effectors mediating this response are poorly defined. By simulating chronic activation of PI3K signaling experimentally, combined with three-dimensional (3...

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Bibliographic Details
Main Authors: Leenders, Frauke, Möpert, Kristin, Schmiedeknecht, Anett, Santel, Ansgar, Czauderna, Frank, Aleku, Manuela, Penschuck, Silke, Dames, Sibylle, Sternberger, Maria, Röhl, Thomas, Wellmann, Axel, Arnold, Wolfgang, Giese, Klaus, Kaufmann, Jörg, Klippel, Anke
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC514518/
https://ncbi.nlm.nih.gov/pubmed/15282551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600345
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