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Inducible shRNA expression for application in a prostate cancer mouse model

RNA interference (RNAi) is a powerful tool to induce loss-of-function phenotypes by inhibiting gene expression post-transcriptionally. Synthetic short interfering RNAs (siRNAs) as well as vector-based siRNA expression systems have been used successfully to silence gene expression in a variety of bio...

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Detalhes bibliográficos
Main Authors: Czauderna, Frank, Santel, Ansgar, Hinz, Michael, Fechtner, Melanie, Durieux, Birgit, Fisch, Gerald, Leenders, Frauke, Arnold, Wolfgang, Giese, Klaus, Klippel, Anke, Kaufmann, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC275484/
https://ncbi.nlm.nih.gov/pubmed/14576327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng127
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