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SspB delivery of substrates for ClpXP proteolysis probed by the design of improved degradation tags
The ssrA-degradation tag sequence contains contiguous binding sites for the SspB adaptor and the ClpX component of the ClpXP protease. Although SspB normally enhances ClpXP degradation of ssrA-tagged substrates, it inhibits proteolysis under conditions that prevent tethering to ClpX. By increasing t...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC514447/ https://ncbi.nlm.nih.gov/pubmed/15297609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404733101 |
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