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Importance in catalysis of a magnesium ion with very low affinity for a hammerhead ribozyme

Available evidence suggests that Mg(2+) ions are involved in reactions catalyzed by hammerhead ribozymes. However, the activity in the presence of exclusively monovalent ions led us to question whether divalent metal ions really function as catalysts when they are present. We investigated ribozyme a...

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Autori principali: Inoue, Atsushi, Takagi, Yasuomi, Taira, Kazunari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC514375/
https://ncbi.nlm.nih.gov/pubmed/15302920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh753
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